Immunogenicity of Three Different Influenza Vaccines against Homologous and Heterologous Strains in Nursing Home Elderly Residents
المؤلفون المشاركون
Trivello, Renzo
Baldovin, Tatjana
Angiolelli, Gabriele
Busana, Marta Cecilia
Pellegrini, Michele
Floreani, Annarosa
Bertoncello, Chiara
Baldo, Vincenzo
Majori, Silvia
المصدر
Clinical and Developmental Immunology
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-03-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We studied whether MF59-adjuvanted influenza vaccine improves immunity against drifted influenza strains in institutionalised elderly with underling chronic health conditions.
Sera from a randomized study, comparing MF59-adjuvanted (Sub/MF59, n=72), virosomal (SVV, n=39), and split (n=88) vaccines, were retested using a hemagglutination inhibition (HI) assay against homologous (Northern Hemisphere [NH] 1998/99) and drifted (NH 2006/07) strains.
Corrected postvaccination HI antibody titres were significantly higher with Sub/MF59 than SVV for all strains; GMTs against homologous A/H3N2 and B and both drifted A strains were significantly higher for Sub/MF59 than split.
Seroprotection rates and mean-fold titer increases were generally higher with Sub/MF59 for all A influenza strains.
MF59-adjuvanted influenza vaccine induced greater and broader immune responses in elderly people with chronic conditions, than conventional virosomal and split vaccines, particularly for A/H1 and A/H3 strains, potentially giving clinical benefit in seasons where antigenic mismatch occurs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baldo, Vincenzo& Baldovin, Tatjana& Pellegrini, Michele& Angiolelli, Gabriele& Majori, Silvia& Floreani, Annarosa…[et al.]. 2010. Immunogenicity of Three Different Influenza Vaccines against Homologous and Heterologous Strains in Nursing Home Elderly Residents. Clinical and Developmental Immunology،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-477958
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baldo, Vincenzo…[et al.]. Immunogenicity of Three Different Influenza Vaccines against Homologous and Heterologous Strains in Nursing Home Elderly Residents. Clinical and Developmental Immunology No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-477958
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baldo, Vincenzo& Baldovin, Tatjana& Pellegrini, Michele& Angiolelli, Gabriele& Majori, Silvia& Floreani, Annarosa…[et al.]. Immunogenicity of Three Different Influenza Vaccines against Homologous and Heterologous Strains in Nursing Home Elderly Residents. Clinical and Developmental Immunology. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-477958
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-477958
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر