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Preoperative Erythrocyte Sedimentation Rate Independently Predicts Overall Survival in Localized Renal Cell Carcinoma following Radical Nephrectomy
المؤلفون المشاركون
Harris, Wayne B.
Johnson, Timothy V.
Kucuk, Omer
Pattaras, John G.
Nieh, Peter T.
DeRosa, Austin B.
Cross, Brian W.
Ogan, Kenneth
Master, Viraj A.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
To determine the relationship between preoperative erythrocyte sedimentation rate (ESR) and overall survival in localized renal cell carcinoma (RCC) following nephrectomy.
Methods.
167 patients undergoing nephrectomy for localized RCC had ESR levels measured preoperatively.
Receiver Operating Characteristics curves were used to determine Area Under the Curve and relative sensitivity and specificity of preoperative ESR in predicting overall survival.
Cut-offs for low (0.0–20.0 mm/hr), intermediate (20.1–50.0 mm/hr), and high risk (>50.0 mm/hr) groups were created.
Kaplan-Meier analysis was conducted to assess the univariate impact of these ESR-based groups on overall survival.
Univariate and multivariate Cox regression analysis was conducted to assess the potential of these groups to predict overall survival, adjusting for other patient and tumor characteristics.
Results.
Overall, 55.2% were low risk, while 27.0% and 17.8% were intermediate and high risk, respectively.
Median (95% CI) survival was 44.1 (42.6–45.5) months, 35.5 (32.3–38.8) months, and 32.1 (25.5–38.6) months, respectively.
After controlling for other patient and tumor characteristics, intermediate and high risk groups experienced a 4.5-fold (HR: 4.509, 95% CI: 0.735–27.649) and 18.5-fold (HR: 18.531, 95% CI: 2.117–162.228) increased risk of overall mortality, respectively.
Conclusion.
Preoperative ESR values represent a robust predictor of overall survival following nephrectomy in localized RCC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cross, Brian W.& Johnson, Timothy V.& DeRosa, Austin B.& Ogan, Kenneth& Pattaras, John G.& Nieh, Peter T.…[et al.]. 2012. Preoperative Erythrocyte Sedimentation Rate Independently Predicts Overall Survival in Localized Renal Cell Carcinoma following Radical Nephrectomy. International Journal of Surgical Oncology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-478596
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cross, Brian W.…[et al.]. Preoperative Erythrocyte Sedimentation Rate Independently Predicts Overall Survival in Localized Renal Cell Carcinoma following Radical Nephrectomy. International Journal of Surgical Oncology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-478596
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cross, Brian W.& Johnson, Timothy V.& DeRosa, Austin B.& Ogan, Kenneth& Pattaras, John G.& Nieh, Peter T.…[et al.]. Preoperative Erythrocyte Sedimentation Rate Independently Predicts Overall Survival in Localized Renal Cell Carcinoma following Radical Nephrectomy. International Journal of Surgical Oncology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-478596
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-478596
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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