Axillary Dissection in Breast Cancer Patients with Metastatic Sentinel Node : To Do or Not to Do? Suggestions from Our Series

الملخص EN

Several studies have put to question and evaluated the indication and prognosis of sentinel lymph node biopsy (SNLB) as sole treatment in human breast cancer.

We reviewed 1588 patients who underwent axillary surgery.

In 239 patients, axillary lymph node dissection (ALND) was performed following positive fine needle aspiration cytology (FNAC), and, in 299 cases, ALND was executed after positive SNLB.

The most dramatic result from our data is that patients with either micrometastasis of the sentinel lymph node (SLN) or only metastatic SLN have, respectively, an 84.5% and a 75.0% chance of having no other nodal involvement.

We believe a more refined patient selection is neccessary when considering ALND.

Where the primary tumor is larger than 5 cm, where radio or adjuvant therapies are not indicated, in cases of FNAC+ nodes, and in cases presenting more than one metastatic sentinel node, we prefer to carry out ALND.

Having thus said, however, our data suggests that it is wise not to perform ALND in almost all cases presenting positive SLNs.