A Proteome Reference Map of the Causative Agent of Melioidosis Burkholderia pseudomallei

الملخص EN

Burkholderia pseudomallei is the etiologic agent of melioidosis.

Using 2DE and MALDI-TOF MS, we report here a proteome reference map constructed from early stationary phase, a bacterial adaptation process.

We identified 282 protein spots representing 220 ORFs; many of them have been implicated in bacterial pathogenesis.

Up to 20% of identified ORFs belong to post-translational modification and stress responses.

The proteome reference map will support future analysis of the bacterial gene and environmental regulation and facilitate comparative proteomics with its sibling species.