Relationship between Adiponectin Level, Insulin Sensitivity, and Metabolic Syndrome in Type 1 Diabetic Patients
المؤلفون المشاركون
Bulum, Tomislav
Duvnjak, Lea
Zibar, Karin
Blaslov, Kristina
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-07-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
Adiponectin is known to be decreased in insulin resistance (IR) and metabolic syndrome (MS) which can be present in patients with type 1 diabetes mellitus (T1DM).
The aim of this study was to evaluate the relationship between adiponectin level, MS, and insulin sensitivity in T1DM.
Research Design and Methods.
The study included 77 T1DM patients divided into two groups based on the total plasma adiponectin median value.
Insulin sensitivity was calculated with the equation for eGDR, and MS was defined according to International Diabetes Federation criteria.
Results.
Patients with higher adiponectin level (n=39) had significantly lower waist circumference (P<0.002), fasting venous glucose levels (P<0.001), higher HDL3-cholesterol (P=0.011), and eGDR (P=0.003) in comparison to the group with lower adiponectin who showed higher prevalence of MS (P=0.045).
eGDR increased for 1.09 mg/kg−1 min−1 by each increase of 1 µg/mL total fasting plasma adiponectin (P=0.003).
In the logistic regression model, adiponectin was inversely associated with the presence of MS (P=0.014).
Conclusion.
Higher adiponectin concentration is associated with lower prevalence of MS in T1DM.
Whether higher adiponectin concentration has a protective role in the development of the MS in T1DM needs to be clarified in future follow-up studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Blaslov, Kristina& Bulum, Tomislav& Zibar, Karin& Duvnjak, Lea. 2013. Relationship between Adiponectin Level, Insulin Sensitivity, and Metabolic Syndrome in Type 1 Diabetic Patients. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-479468
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Blaslov, Kristina…[et al.]. Relationship between Adiponectin Level, Insulin Sensitivity, and Metabolic Syndrome in Type 1 Diabetic Patients. International Journal of Endocrinology No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-479468
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Blaslov, Kristina& Bulum, Tomislav& Zibar, Karin& Duvnjak, Lea. Relationship between Adiponectin Level, Insulin Sensitivity, and Metabolic Syndrome in Type 1 Diabetic Patients. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-479468
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-479468
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر