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The Suckling Rat as a Model for Immunonutrition Studies in Early Life
المؤلفون المشاركون
Castell Escuer, Margarida
Pérez-Cano, Francisco J.
Castellote, Cristina
Franch, Àngels
المصدر
Clinical and Developmental Immunology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-31
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Diet plays a crucial role in maintaining optimal immune function.
Research demonstrates the immunomodulatory properties and mechanisms of particular nutrients; however, these aspects are studied less in early life, when diet may exert an important role in the immune development of the neonate.
Besides the limited data from epidemiological and human interventional trials in early life, animal models hold the key to increase the current knowledge about this interaction in this particular period.
This paper reports the potential of the suckling rat as a model for immunonutrition studies in early life.
In particular, it describes the main changes in the systemic and mucosal immune system development during rat suckling and allows some of these elements to be established as target biomarkers for studying the influence of particular nutrients.
Different approaches to evaluate these immune effects, including the manipulation of the maternal diet during gestation and/or lactation or feeding the nutrient directly to the pups, are also described in detail.
In summary, this paper provides investigators with useful tools for better designing experimental approaches focused on nutrition in early life for programming and immune development by using the suckling rat as a model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pérez-Cano, Francisco J.& Franch, Àngels& Castellote, Cristina& Castell Escuer, Margarida. 2012. The Suckling Rat as a Model for Immunonutrition Studies in Early Life. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-479603
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pérez-Cano, Francisco J.…[et al.]. The Suckling Rat as a Model for Immunonutrition Studies in Early Life. Clinical and Developmental Immunology No. 2012 (2012), pp.1-16.
https://search.emarefa.net/detail/BIM-479603
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pérez-Cano, Francisco J.& Franch, Àngels& Castellote, Cristina& Castell Escuer, Margarida. The Suckling Rat as a Model for Immunonutrition Studies in Early Life. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-16.
https://search.emarefa.net/detail/BIM-479603
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-479603
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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