Prognostic Factors and Metastatic Patterns in Primary MyxoidRound-Cell Liposarcoma
المؤلفون المشاركون
Spooner, David
Abudu, Adesegun
Carter, S. R.
Sumathi, Vaiyapuri
Tillman, Roger M.
Jeys, L. M.
Grimer, Robert J.
Haniball, J.
Kindblom, L.-G.
Peake, David
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-28
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
This study aimed to investigate prognostic factors for patients with myxoid/round-cell liposarcoma (MRCLS), in particular the significance of the round cell component, and to identify metastatic patterns as well as possibly suggest a suitable strategy for followup.
Methods.
Clinical, morphologic, and follow-up data from 160 patients with MRCLS was reviewed and statistically analysed.
Results.
Of 130 tumours with the round cell component evaluated, 61 had no round cell component, 27 had <5% round cell component, and 42 had >5%.
All patients underwent surgical excision, 15 requiring amputation.
107 patients received adjuvant radiotherapy.
Local recurrence occurred in 19 patients (12%), predominantly in patients with marginal or intralesional margins and a round cell component.
Overall disease specific survival was 75% at 5 years and 56% at 10 years and was related to the proportion of round cell component.
Of 52 patients who developed metastases, 38 (73%) had purely extrapulmonary metastases.
We could not identify any factors predicting the site of metastases developing.
Conclusions.
The occurrence of any round cell component is the most important adverse prognostic factor for patients with MRCLS; patients with >5% round cell component are at higher risk of local recurrence, metastasis and tumour-related death and should be considered for adjuvant radiotherapy and possibly chemotherapy.
The best method of monitoring extrapulmonary metastases remains to be established.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Haniball, J.& Sumathi, Vaiyapuri& Kindblom, L.-G.& Abudu, Adesegun& Carter, S. R.& Tillman, Roger M.…[et al.]. 2011. Prognostic Factors and Metastatic Patterns in Primary MyxoidRound-Cell Liposarcoma. Sarcoma،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-479677
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Haniball, J.…[et al.]. Prognostic Factors and Metastatic Patterns in Primary MyxoidRound-Cell Liposarcoma. Sarcoma No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-479677
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Haniball, J.& Sumathi, Vaiyapuri& Kindblom, L.-G.& Abudu, Adesegun& Carter, S. R.& Tillman, Roger M.…[et al.]. Prognostic Factors and Metastatic Patterns in Primary MyxoidRound-Cell Liposarcoma. Sarcoma. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-479677
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-479677
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر