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In Vitro Chloroquine Resistance in Plasmodium falciparum Isolates from Tertiary Care Hospital
المؤلفون المشاركون
Ashfaq, Mohammad
Shujatullah, Fatima
Khatoon, Abida
Khan, Parvez A.
Khan, Haris M.
المصدر
Malaria Research and Treatment
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-24
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Chloroquine (CQ) has been the mainstay of treatment of malaria for decades.
This cost-effective and safe drug has become ineffective for treatment of falciparum malaria in many parts of the world due to development of resistance by the parasite.
In addition CQ is not gametocytocidal for P.
falciparum and thus cannot block transmission.
The extent of problem of chloroquine resistance in P.
falciparum is increasing every year.
The study was done in period of 2 years.
A total of 5653 specimens were examined for malarial infection by employing different diagnostic modalities.
Four hundred and thirty-five were found to be positive for P.
falciparum by using different diagnostic techniques.
All positive specimens were cultured on RPMI 1640 medium; only 108 were found to be culture positive.
Sensitivity of isolates to chloroquine was done using Mark III WHO sensitivity plates.
The prevalence of malaria infection was found 9.54% in 2010.
There were schizont formation at 8 pmol/liter or more of chloroquine concentration in 26 isolates.
The emergence of chloroquine (CQ) resistance pattern in Aligarh isolates increases.
Antimalarial agents should be used with caution; monotherapies should be avoided.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shujatullah, Fatima& Khan, Haris M.& Khatoon, Abida& Khan, Parvez A.& Ashfaq, Mohammad. 2012. In Vitro Chloroquine Resistance in Plasmodium falciparum Isolates from Tertiary Care Hospital. Malaria Research and Treatment،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-479710
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shujatullah, Fatima…[et al.]. In Vitro Chloroquine Resistance in Plasmodium falciparum Isolates from Tertiary Care Hospital. Malaria Research and Treatment No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-479710
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shujatullah, Fatima& Khan, Haris M.& Khatoon, Abida& Khan, Parvez A.& Ashfaq, Mohammad. In Vitro Chloroquine Resistance in Plasmodium falciparum Isolates from Tertiary Care Hospital. Malaria Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-479710
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-479710
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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