Fibronectin Adsorption to Nanopatterned Silicon Surfaces

الملخص EN

The possibility of using surface topography for guidance of different biological molecules and cells is a relevant topic that can be applied to a wide research activity.

This study investigated the adsorption of fibronectin to a diffraction grated silicon surface.

The rectangular grating profile featured a controlled surface with 350 nm period and a corrugation depth of 90 nm.

Results demonstrated that the controlled surface had a significantly positive effect on the fibronectin binding.

Thus, nanoscale surface topography can enhance fibronectin binding.