Levosimendan as Treatment Option in Severe Verapamil Intoxication : A Case Report and Review of the Literature

المؤلفون المشاركون

Marsch, Stephan C.
Osthoff, Mirjam
Hunziker, Patrick R.
Bernsmeier, Christine

المصدر

Case Reports in Medicine

العدد

المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-3، 3ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2010-08-11

دولة النشر

مصر

عدد الصفحات

3

التخصصات الرئيسية

الطب البشري

الملخص EN

Cardiovascular shock due to verapamil intoxication is often refractory to standard resuscitation methods.

Recommended therapy includes prevention of further absorption of the drug, inotropic therapy, calcium gluconate, and hyperinsulinemia/euglycemia therapy.

Often further measures are needed such as ventricular pacing or mechanical circulatory support.

Still, mortality remains high.

Levosimendan, an inotropic agent, that enhances myofilament response to calcium, increases myocardial contraction and could therefore be beneficial in verapamil intoxication.

Here, we report the case of a 60-year-old patient with clinically severe verapamil poisoning who presented with shock, bradycardia, and sopor.

Standard therapy including high-dose inotropes failed to ameliorate the signs of intoxication.

But additional therapy with levosimendan led to rapid improvement.

Based on this observation, the literature is reviewed focusing on utilization of levosimendan in the treatment of calcium channel blocker overdose.

We suggest to consider levosimendan as additional treatment option in patients with cardiovascular shock due to verapamil intoxication that are refractory to standard management.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Osthoff, Mirjam& Bernsmeier, Christine& Marsch, Stephan C.& Hunziker, Patrick R.. 2010. Levosimendan as Treatment Option in Severe Verapamil Intoxication : A Case Report and Review of the Literature. Case Reports in Medicine،Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-480409

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Osthoff, Mirjam…[et al.]. Levosimendan as Treatment Option in Severe Verapamil Intoxication : A Case Report and Review of the Literature. Case Reports in Medicine No. 2010 (2010), pp.1-3.
https://search.emarefa.net/detail/BIM-480409

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Osthoff, Mirjam& Bernsmeier, Christine& Marsch, Stephan C.& Hunziker, Patrick R.. Levosimendan as Treatment Option in Severe Verapamil Intoxication : A Case Report and Review of the Literature. Case Reports in Medicine. 2010. Vol. 2010, no. 2010, pp.1-3.
https://search.emarefa.net/detail/BIM-480409

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-480409