Treatment Outcomes in a Decentralized Antiretroviral Therapy Program : A Comparison of Two Levels of Care in North Central Nigeria
المؤلفون المشاركون
Okonkwo, Prosper
Imade, Godwin E.
Oyebode, Tinuade A.
Agbaji, Oche O.
Idoko, John A.
Yohanna, Stephen
Agaba, Patricia A.
Banigbe, Bolanle
Adeola, Juliet
Kanki, Phyllis J.
Sagay, Atiene S.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-16
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Decentralization of antiretroviral therapy (ART) services is a key strategy to achieving universal access to treatment for people living with HIV/AIDS.
Our objective was to assess clinical and laboratory outcomes within a decentralized program in Nigeria.
Methods.
Using a tiered hub-and-spoke model to decentralize services, a tertiary hospital scaled down services to 13 secondary-level hospitals using national and program guidelines.
We obtained sociodemographic, clinical, and immunovirologic data on previously antiretroviral drug naïve patients aged ≥15 years that received HAART for at least 6 months and compared treatment outcomes between the prime and satellite sites.
Results.
Out of 7,747 patients, 3729 (48.1%) were enrolled at the satellites while on HAART, prime site patients achieved better immune reconstitution based on CD4+ cell counts at 12 (P<0.001) and 24 weeks (P<0.001) with similar responses at 48 weeks (P=0.11) and higher rates of viral suppression (<400 c/mL) at 12 (P<0.001) and 48 weeks (P=0.03), but similar responses at 24 weeks (P=0.21).
Mortality was 2.3% versus 5.0% (P<0.001) at prime and satellite sites, while transfer rate was 8.7% versus 5.5% (P=0.001) at prime and satellites.
Conclusion.
ART decentralization is feasible in resource-limited settings, but efforts have to be intensified to maintain good quality of care.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Okonkwo, Prosper& Sagay, Atiene S.& Agaba, Patricia A.& Yohanna, Stephen& Agbaji, Oche O.& Imade, Godwin E.…[et al.]. 2014. Treatment Outcomes in a Decentralized Antiretroviral Therapy Program : A Comparison of Two Levels of Care in North Central Nigeria. AIDS Research and Treatment،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-480788
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Okonkwo, Prosper…[et al.]. Treatment Outcomes in a Decentralized Antiretroviral Therapy Program : A Comparison of Two Levels of Care in North Central Nigeria. AIDS Research and Treatment No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-480788
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Okonkwo, Prosper& Sagay, Atiene S.& Agaba, Patricia A.& Yohanna, Stephen& Agbaji, Oche O.& Imade, Godwin E.…[et al.]. Treatment Outcomes in a Decentralized Antiretroviral Therapy Program : A Comparison of Two Levels of Care in North Central Nigeria. AIDS Research and Treatment. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-480788
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480788
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر