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AIDS-Related EBV-Associated Smooth Muscle Tumors : A Review of 64 Published Cases
المؤلفون المشاركون
Purgina, Bibianna
Pantanowitz, Liron
Rao, Uma N. M.
Miettinen, Markku
المصدر
Pathology Research International
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-03-10
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The number of reported cases of smooth muscle tumor (SMT) arising in patients with AIDS has been increasing since the mid-1990s.
The aim of this study is to characterize the epidemiology, clinical manifestations, pathologic features, prognosis and, management of Epstein-Barr virus-related SMT (EBV-SMT) in patients with AIDS.
An English language literature search identified 53 articles including 64 reported cases of EBV-SMT.
The majority of these reports involved patients who were young, severely immunosuppressed, and had multifocal tumors.
The central nervous system was the most common site to be involved.
Histologically, tumors had smooth muscle features and were immunoreactive for muscle markers and all but two tumors demonstrated the presence of EBV by either immunohistochemistry, in situ hybridization, and/or PCR.
While mitoses and/or necrosis were used to separate leiomyoma from leiomyosarcoma, these features did not correlate with clinical outcome.
Treatment included primarily resection, and less often radiotherapy, chemotherapy and highly active antiretroviral therapy (HAART).
Overall, EBV-SMTs appear to have variable aggressiveness and clinical outcome and may exhibit a more favorable prognosis compared to conventional leiomyosarcoma.
Tumor-related death from EBV-SMT occurred in only 4 of 51 patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Purgina, Bibianna& Rao, Uma N. M.& Miettinen, Markku& Pantanowitz, Liron. 2011. AIDS-Related EBV-Associated Smooth Muscle Tumors : A Review of 64 Published Cases. Pathology Research International،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-480876
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Purgina, Bibianna…[et al.]. AIDS-Related EBV-Associated Smooth Muscle Tumors : A Review of 64 Published Cases. Pathology Research International No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-480876
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Purgina, Bibianna& Rao, Uma N. M.& Miettinen, Markku& Pantanowitz, Liron. AIDS-Related EBV-Associated Smooth Muscle Tumors : A Review of 64 Published Cases. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-480876
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-480876
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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