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The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination
المؤلفون المشاركون
Shibahara, Naotoshi
Koizumi, Keiichi
Origasa, Hideki
Sakurai, Hiroaki
Saiki, Ikuo
Inujima, Akiko
Shimada, Yutaka
Raimura, Masaki
Goto, Hirozo
Fujimoto, Makoto
Oka, Hiroshi
Inoue, Hiroki
Namiki, Takao
Hikiami, Hiroaki
Sakai, Shinya
Kogure, Toshiaki
Tatsumi, Takeshi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We have performed a broad-ranging analysis of the adjuvant effect of a Kampo medicine, juzentaihoto (JTT), on influenza vaccination in a multicenter randomized controlled trial.
In this study, the enhancing effect of JTT on antibody titer after influenza vaccination was studied for 28 weeks in elderly people who were in the high-risk group for influenza infection.
In total, 91 subjects over 65 years old were recruited from four long-term-care facilities located in Chiba, Gunma, and Toyama prefectures in Japan.
Participants were randomly assigned to the JTT and the control groups.
Blood samples were taken at 4 weeks before vaccination, at the time of vaccination, and then at 4, 8, 12, and 24 weeks after vaccination.
The hemagglutination inhibition (HI) titers against A/California/7/2009 (H1N1), A/Victoria/210/2009 (H3N2), and B/Brisbane/60/2008 were then manually measured.
A significant increase in HI titer against H3N2 was observed at week 8 after vaccination in the JTT group compared with the control group (P=0.0229), and the HI titer of the JTT group significantly increased from 4 to 24 weeks (P=0.0468), compared with the control group.
In conclusion, our results indicated that JTT increased and prolonged antibody production against A/Victoria/210/2009 (H3N2), in particular, after influenza vaccination.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Saiki, Ikuo& Koizumi, Keiichi& Goto, Hirozo& Inujima, Akiko& Namiki, Takao& Raimura, Masaki…[et al.]. 2013. The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481363
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Saiki, Ikuo…[et al.]. The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-481363
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Saiki, Ikuo& Koizumi, Keiichi& Goto, Hirozo& Inujima, Akiko& Namiki, Takao& Raimura, Masaki…[et al.]. The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-481363
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481363
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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