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Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy : A Case Study
المؤلفون المشاركون
Miura, Katsutoshi
Ogura, Hiroyuki
Teruya, Chikako
Hatsuko, Nasu
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Lymphocytic mastopathy or diabetic mastopathy is a benign breast disease characterized by dense fibrosis, lobular atrophy, and aggregates of lymphocytes in a periductal and perilobular distribution.
The condition usually affects women with a long history of diabetes mellitus (DM) and also those with autoimmune disorders.
While the pathogenesis is unknown, a particular type of class II human leukocyte antigen has been associated with this disease.
Herein, we report a case of diabetic mastopathy which clinically and radiologically mimicked primary breast neoplasms.
The patient was a 74-year-old woman with a 31-year history of DM type II who presented with multiple firm lumps in bilateral breasts.
Findings from mammography, ultrasonography, and magnetic resonance imaging of the breasts revealed an abnormal appearance which suspiciously resembled malignancy.
An aspiration cytology specimen showed atypical accumulation of lymphoid cells, leading us to suspect lymphoma.
Histology of an excisional biopsy showed the characteristic appearance of lymphocytic mastopathy, which predominantly consisted of B-lymphocytes.
Autoantibodies in her serum reacted positively against her ductal epithelium as well as other diabetic and nondiabetic breast ductal cells.
An antigen absorption test with insulin revealed attenuating intensity according to insulin concentration.
These anti-insulin antibodies produced in the DM patient may cause ductitis because of antigen cross-reactivity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Miura, Katsutoshi& Teruya, Chikako& Hatsuko, Nasu& Ogura, Hiroyuki. 2012. Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy : A Case Study. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-481452
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Miura, Katsutoshi…[et al.]. Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy : A Case Study. Case Reports in Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-481452
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Miura, Katsutoshi& Teruya, Chikako& Hatsuko, Nasu& Ogura, Hiroyuki. Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy : A Case Study. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-481452
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481452
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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