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Reduced Bone and Body Mass in Young Male Rats Exposed to Lead
المؤلفون المشاركون
Augusto Tocchini de Figueiredo, Fellipe
Ramos, Junia
Gerlach, Raquel Fernanda
de Souza Guerra, Carolina
Andreia Mesquita Silva da Veiga, Márcia
Reiko Kawakita, Erika
Issa, João Paulo Mardegan
Venancio Nakadi, Flavio
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The aim of this study was to see whether there would be differences in whole blood versus tibia lead concentrations over time in growing rats prenatally.
Lead was given in the drinking water at 30 mg/L from the time the dams were pregnant until offspring was 28- or 60-day-old.
Concentrations of lead were measured in whole blood and in tibia after 28 (28D) and 60 days (60D) in control (C) and in lead-exposed animals (Pb).
Lead measurements were made by GF-AAS.
There was no significant difference (P>0.05) in the concentration of whole blood lead between Pb-28D (8.0±1.1 μg/dL) and Pb-60D (7.2±0.89 μg/dL), while both significantly varied (P<0.01) from controls (0.2 μg/dL).
Bone lead concentrations significantly varied between the Pb-28D (8.02±1.12 μg/g) and the Pb-60D (43.3±13.26 μg/g) lead-exposed groups (P<0.01), while those exposed groups were also significantly higher (P<0.0001) than the 28D and 60D control groups (Pb < 1 μg/g).
The Pb-60D group showed a 25% decrease in tibia mass as compared to the respective control.
The five times higher amount of lead found in the bone of older animals (Pb-60D versus Pb-28D), which reinforces the importance of using bone lead as an exposure biomarker.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Augusto Tocchini de Figueiredo, Fellipe& Gerlach, Raquel Fernanda& Andreia Mesquita Silva da Veiga, Márcia& Venancio Nakadi, Flavio& Ramos, Junia& Reiko Kawakita, Erika…[et al.]. 2014. Reduced Bone and Body Mass in Young Male Rats Exposed to Lead. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-481635
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Augusto Tocchini de Figueiredo, Fellipe…[et al.]. Reduced Bone and Body Mass in Young Male Rats Exposed to Lead. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-481635
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Augusto Tocchini de Figueiredo, Fellipe& Gerlach, Raquel Fernanda& Andreia Mesquita Silva da Veiga, Márcia& Venancio Nakadi, Flavio& Ramos, Junia& Reiko Kawakita, Erika…[et al.]. Reduced Bone and Body Mass in Young Male Rats Exposed to Lead. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-481635
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481635
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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