Antiviral and Virucidal Activities of Nα-Cocoyl-L-Arginine Ethyl Ester
المؤلفون المشاركون
Yamasaki, Hisashi
Tsujimoto, Kazuko
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Various amino acid-derived compounds, for example, Nα-Cocoyl-L-arginine ethyl ester (CAE), alkyloxyhydroxylpropylarginine, arginine cocoate, and cocoyl glycine potassium salt (Amilite), were examined for their virucidal activities against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), influenza A virus (IAV), and poliovirus type 1 (PV-1) in comparison to benzalkonium chloride (BKC) and sodium dodecylsulfate (SDS) as a cationic and anionic control detergent and also to other commercially available disinfectants.
While these amino acid-derived compounds were all effective against HSV-1 and HSV-2, CAE and Amilite were the most effective.
These two compounds were, however, not as effective against IAV, another enveloped virus, as against HSV.
Cytotoxicity of CAE was weak; at 0.012%, only 5% of the cells were killed under the conditions, in which 100% cells were killed by either SDS or BKC.
In addition to these direct virucidal effects, CAE inhibited the virus growth in the HSV-1- or PV-1-infected cells even at 0.01%.
These results suggest a potential application of CAE as a therapeutic or preventive medicine against HSV superficial infection at body surface.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yamasaki, Hisashi& Tsujimoto, Kazuko. 2011. Antiviral and Virucidal Activities of Nα-Cocoyl-L-Arginine Ethyl Ester. Advances in Virology،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-481812
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yamasaki, Hisashi& Tsujimoto, Kazuko. Antiviral and Virucidal Activities of Nα-Cocoyl-L-Arginine Ethyl Ester. Advances in Virology No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-481812
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yamasaki, Hisashi& Tsujimoto, Kazuko. Antiviral and Virucidal Activities of Nα-Cocoyl-L-Arginine Ethyl Ester. Advances in Virology. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-481812
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481812
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر