New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma : A Case Report and Review of the Literature

الملخص EN

Prolactinomas are the commonest pituitary adenomas and the major pathological cause of hyperprolactinaemia.

Symptomatic prolactinomas are treated mainly by dopamine agonists; surgery and radiotherapy are options for nonresponders.

Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems.

We report a case of a 39-year-old schizophrenic male patient that was diagnosed with a macroprolactinoma 8 years after his first psychotic episode.

The association of Schizophrenia and prolactinoma represents a clinical challenge once the treatment of one disease can exacerbate the symptoms of the other.