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Significance of Lewis Phenotyping Using Saliva and Gastric Tissue : Comparison with the Lewis Phenotype Inferred from Lewis and Secretor Genotypes
المؤلفون المشاركون
Hwang, Sang Mee
Kim, Taek Soo
Park, Kyoung Un
Hong, Yun Ji
Song, Eun Young
Song, Junghan
Han, Kyou-Sup
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Lewis phenotypes using various types of specimen were compared with the Lewis phenotype predicted from Lewis and Secretor genotypes.
This is the first logical step in explaining the association between the Lewis expression and Helicobacter pylori.
We performed a study of the followings on 209 patients who underwent routine gastroscopy: erythrocyte and saliva Lewis phenotyping, gastric Lewis phenotyping by the tissue array, and the Lewis and Secretor genes genotyping.
The results of phenotyping were as follows [Le(a−b−), Le(a+b−), Le(a−b+), and Le(a+b+), respectively, in order]: erythrocyte (12.4%, 25.8%, 61.2%, and 0.5%); saliva (2.4%, 27.3%, 70.3%, and 0.0%); gastric mucosa (8.1%, 6.7%, 45.5%, and 39.7%).
The frequency of Le, le59/508, le59/1067 , and le59 alleles was 74.6%, 21.3%, 3.1%, and 1.0%, respectively, among 418 alleles.
The saliva Lewis phenotype was completely consistent with the Lewis phenotype inferred from Lewis and Secretor genotypes, but that of gastric mucosa could not be predicted from genotypes.
Lewis phenotyping using erythrocytes is only adequate for transfusion needs.
Saliva testing for the Lewis phenotype is a more reliable method for determining the peripheral Lewis phenotype of an individual and the gastric Lewis phenotype must be used for the study on the association between Helicobacter pylori and the Lewis phenotype.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hong, Yun Ji& Hwang, Sang Mee& Kim, Taek Soo& Song, Eun Young& Park, Kyoung Un& Song, Junghan…[et al.]. 2014. Significance of Lewis Phenotyping Using Saliva and Gastric Tissue : Comparison with the Lewis Phenotype Inferred from Lewis and Secretor Genotypes. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-481888
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hong, Yun Ji…[et al.]. Significance of Lewis Phenotyping Using Saliva and Gastric Tissue : Comparison with the Lewis Phenotype Inferred from Lewis and Secretor Genotypes. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-481888
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hong, Yun Ji& Hwang, Sang Mee& Kim, Taek Soo& Song, Eun Young& Park, Kyoung Un& Song, Junghan…[et al.]. Significance of Lewis Phenotyping Using Saliva and Gastric Tissue : Comparison with the Lewis Phenotype Inferred from Lewis and Secretor Genotypes. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-481888
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-481888
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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