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HOMA-AD in Assessing Insulin Resistance in Lean Noncirrhotic HCV Outpatients
المؤلفون المشاركون
Alvares-da-Silva, Mario Reis
Michalczuk, Matheus Truccolo
Birkhan, Oscar
Kappel, Camila Rippol
Bragança, Ana Carolina
المصدر
International Journal of Hepatology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-16
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
There is an association between HCV and insulin resistance (IR), which is currently assessed by HOMA-IR.
There is evidence that HOMA-adiponectin (HOMA-AD) is more accurate, but its role in HCV patients is unknown.
The purpose of this study was to evaluate IR in an HCV sample and controls, in order to compare the accuracy of HOMA-IR and HOMA-AD.
Methods.
Ninety-four HCV outpatients aged <60 years who met the criteria of nondiabetic, nonobese, noncirrhotic, and nonalcohol abusers were included and compared to 29 controls.
Fasting glucose, insulin, adiponectin, and lipid profiles were determined.
IR was estimated by HOMA-IR and HOMA-AD.
Results.
The groups were similar regarding sex and BMI, but the HCV patients were older.
The median insulin level was higher in the HCV group (8.6 mU/mL (6.5–13.7) versus 6.5 (4.3–10.7), P=0.004), as was median HOMA-IR (1.94 (1.51 to 3.48) versus 1.40 (1.02 to 2.36), P=0.002) and the prevalence of IR (38.3% versus 10.3% (P=0.009)).
No differences were found in adiponectin levels (P=0.294) and HOMA-AD (P=0.393).
Conclusion.
IR is highly prevalent even in low-risk HCV outpatients.
Adiponectin is not influenced by the presence of HCV.
HOMA-AD does not seem to be useful in assessing IR in HCV patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Michalczuk, Matheus Truccolo& Kappel, Camila Rippol& Birkhan, Oscar& Bragança, Ana Carolina& Alvares-da-Silva, Mario Reis. 2012. HOMA-AD in Assessing Insulin Resistance in Lean Noncirrhotic HCV Outpatients. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-482133
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Michalczuk, Matheus Truccolo…[et al.]. HOMA-AD in Assessing Insulin Resistance in Lean Noncirrhotic HCV Outpatients. International Journal of Hepatology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-482133
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Michalczuk, Matheus Truccolo& Kappel, Camila Rippol& Birkhan, Oscar& Bragança, Ana Carolina& Alvares-da-Silva, Mario Reis. HOMA-AD in Assessing Insulin Resistance in Lean Noncirrhotic HCV Outpatients. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-482133
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482133
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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