![](/images/graphics-bg.png)
Physical Properties and Biocompatibility of a Core-Sheath Structure Composite Scaffold for Bone Tissue Engineering In Vitro
المؤلفون المشاركون
Liu, Jian
Wang, Chuangjian
Meng, Guolin
Zhang, Laquan
Xiong, Zuo
المصدر
Journal of Biomedicine and Biotechnology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Scaffolds play a critical role in the practical realization of bone tissue engineering.
The purpose of this study was to assess whether a core-sheath structure composite scaffold possesses admirable physical properties and biocompatibility in vitro.
A novel scaffold composed of poly(lactic-co-glycolic acid)/β-tricalcium phosphate (PLGA/β-TCP) skeleton wrapped with Type I collagen via low-temperature deposition manufacturing (LDM) was prepared, and bone mesenchymal stem cells (BMSCs) were used to evaluate cell behavior on the scaffold.
PLGA/β-TCP skeleton was chosen as the control group.
Physical properties were evaluated by pority ratio, compressive strength, and Young’s modulus.
Scanning electron microscope (SEM) was used to study morphology of cells.
Hydrophilicity was evaluated by water absorption ratio.
Cell proliferation was tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay (MTT).
Osteogenic differentiation of BMSCs was evaluated by alkaline phosphates activity (ALP).
The results indicated that physical properties of the novel scaffold were as good as those of the control group, hydrophilicity was observably better (P<0.01) than that of control group, and abilities of proliferation and osteogenic differentiation of BMSCs on novel scaffold were significantly greater (P<0.05) than those of control group, which suggests that the novel scaffold possesses preferable characteristics and have high value in bone tissue engineering.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Chuangjian& Meng, Guolin& Zhang, Laquan& Xiong, Zuo& Liu, Jian. 2012. Physical Properties and Biocompatibility of a Core-Sheath Structure Composite Scaffold for Bone Tissue Engineering In Vitro. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482286
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Chuangjian…[et al.]. Physical Properties and Biocompatibility of a Core-Sheath Structure Composite Scaffold for Bone Tissue Engineering In Vitro. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-482286
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Chuangjian& Meng, Guolin& Zhang, Laquan& Xiong, Zuo& Liu, Jian. Physical Properties and Biocompatibility of a Core-Sheath Structure Composite Scaffold for Bone Tissue Engineering In Vitro. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-482286
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482286
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)