Concomitant Gastrointestinal Stromal Tumor of the Stomach and Gastric Adenocarcinoma in a Patient with Billroth 2 Resection
المؤلفون المشاركون
Schietroma, Mario
Amicucci, Gianfranco
Sista, Federico
Abruzzese, Valentina
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
With this study we focus on the etiopathogenesis and on the therapy of the simultaneous occurrence of Gastric gastrointestinal stromal tumor (gGIST) and adenocarcinoma of the stomach in a patient with Billroth II gastric resection (BIIGR).
We report the first case of this event and a review of the literature.
Methods.
A 70-year-old man with a BIIGR, affected by adenocarcinoma of the stomach, was successfully treated with total gastrectomy.
The histological examination showed a gastric adenocarcinoma with a synchronous GIST sized 2 cm and S-100, CD117, and CD34 positive.
The mutation of PDGFR gene was detected.
Discussion.
This tumor is a rare mesenchymal neoplasm of the gastrointestinal tract.
Few cases of synchronous gastric adenocarcinoma and GIST are observed in the literature and no case in patients with BIIGR.
Various hypotheses have been proposed to explain this occurrence.
It is frequently attributed to Metallothioneins genes mutations or embryological abnormalities, but this has not been proven yet.
We suggest a hypothesis about the etiopathogenesis of this event in a BIIGR patient.
Conclusion.
GIST may occur synchronously with gastric adenocarcinoma.
This simultaneous occurrence needs more studies to be proven.
The study of Cajal cells’ proliferation signalling is crucial to demonstrate our hypotesis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sista, Federico& Abruzzese, Valentina& Schietroma, Mario& Amicucci, Gianfranco. 2013. Concomitant Gastrointestinal Stromal Tumor of the Stomach and Gastric Adenocarcinoma in a Patient with Billroth 2 Resection. Case Reports in Surgery،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-482713
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sista, Federico…[et al.]. Concomitant Gastrointestinal Stromal Tumor of the Stomach and Gastric Adenocarcinoma in a Patient with Billroth 2 Resection. Case Reports in Surgery No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-482713
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sista, Federico& Abruzzese, Valentina& Schietroma, Mario& Amicucci, Gianfranco. Concomitant Gastrointestinal Stromal Tumor of the Stomach and Gastric Adenocarcinoma in a Patient with Billroth 2 Resection. Case Reports in Surgery. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-482713
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482713
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر