The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia : A Prospective Multicenter Clinical Study
المؤلفون المشاركون
Fuji, Kohzo
Miyazawa, Katsuhito
Boku, Eitetsu
Hirao, Yoshihiko
Tsuji, Hidenori
Fujimoto, Kiyohide
Shibata, Yasuhiro
Ohtani, Mikinobu
Ohashi, Yasuo
Furuya, Ryoji
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-16
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To evaluate the effects of chlormadinone acetate (CMA), progesterone-derived antiandrogen, on lower urinary tract symptoms (LUTS) and erectile functions of benign prostatic hyperplasia (BPH).
Methods.
A multicenter, single-cohort prospective study was conducted.
A total of 114 patients received CMA for 16 weeks.
The endpoints were changes in International Prostate Symptom Scores (IPSS), IPSS-QOL, International Index of Erectile Function-5, Qmax prostate volume, and residual urine volume.
Results.
Significant improvements were observed in IPSS from week 8 to week 48 (32 weeks after treatment).
IPSS-QOL improvements were also significant from week 8 to week 48.
Qmax increased to a maximum at Week 16 and remained elevated throughout the study.
Moreover, a decrease of 25% in prostate volume was observed at Week 16.
IPSS, QOL, and Qmax changes during the study were not different between the previously treated and untreated patients.
IPSS storage subscore changes differed between the age groups.
Few severe adverse reactions were observed, except for erectile dysfunction.
Conclusions.
CMA rapidly and significantly reduced prostate volume and improved voiding and storage symptoms and QOL.
Our results suggest that CMA is safe and beneficial, especially for elderly patients with LUTS associated with BPH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fujimoto, Kiyohide& Hirao, Yoshihiko& Ohashi, Yasuo& Shibata, Yasuhiro& Fuji, Kohzo& Tsuji, Hidenori…[et al.]. 2013. The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia : A Prospective Multicenter Clinical Study. Advances in Urology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-482786
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fujimoto, Kiyohide…[et al.]. The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia : A Prospective Multicenter Clinical Study. Advances in Urology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-482786
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fujimoto, Kiyohide& Hirao, Yoshihiko& Ohashi, Yasuo& Shibata, Yasuhiro& Fuji, Kohzo& Tsuji, Hidenori…[et al.]. The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia : A Prospective Multicenter Clinical Study. Advances in Urology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-482786
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-482786
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر