Serum Antioxidative Enzymes Levels and Oxidative Stress Products in Age-Related Cataract Patients
المؤلفون المشاركون
Han, Tao
Liu, Peipei
Zhang, Xuefei
Sha, Qian
Rong, Shengzhong
Chang, Dong
Pan, Hongzhi
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-05-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Purpose.
To investigate the activity of antioxidative enzymes and the products of oxidative stress in patients with age-related cataracts and compare the findings with those in healthy control subjects.
Method.
Sixty patients with age-related cataract and sixty healthy controls of matched age and gender were included in this study.
Serum samples were obtained to detect the antioxidative enzymes of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), and oxidation degradation products of malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), conjugated diene (CD), advanced oxidation protein products (AOPP), protein carbonyl (PC), and 8-hydroxydeoxyguanosine (8-OHdG).
Results.
Serum SOD, GSH-Px, and CAT activities in cataract group were significantly decreased as compared to the control subjects (P<0.05).
The levels of MDA, 4-HNE, and CD in cataract patients were significantly higher than those in the control subjects (P<0.05, P<0.01).
Cataract patients had higher levels of 8-OHdG, AOPP, and PC with respect to the comparative group of normal subjects (P<0.01).
And there was no statistical significance in concentration of antioxidative enzymes and oxidative stress products in patients with different subtype cataract.
Conclusions.
Oxidative stress is an important risk factor in the development of age-related cataract, and augmentation of the antioxidant defence systems may be of benefit to prevent or delay cataractogenesis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chang, Dong& Zhang, Xuefei& Rong, Shengzhong& Sha, Qian& Liu, Peipei& Han, Tao…[et al.]. 2013. Serum Antioxidative Enzymes Levels and Oxidative Stress Products in Age-Related Cataract Patients. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-483079
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chang, Dong…[et al.]. Serum Antioxidative Enzymes Levels and Oxidative Stress Products in Age-Related Cataract Patients. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-483079
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chang, Dong& Zhang, Xuefei& Rong, Shengzhong& Sha, Qian& Liu, Peipei& Han, Tao…[et al.]. Serum Antioxidative Enzymes Levels and Oxidative Stress Products in Age-Related Cataract Patients. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-483079
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483079
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر