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Hypothermia Improves Oral and Gastric Mucosal Microvascular Oxygenation during Hemorrhagic Shock in Dogs
المؤلفون المشاركون
Swertz, Meike
Schwartges, Ingo
Bauer, Inge
Beck, Christopher
Picker, Olaf
Vollmer, Christian
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-12
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Hypothermia is known to improve tissue function in different organs during physiological and pathological conditions.
The aim of this study was to evaluate the effects of hypothermia on oral and gastric mucosal microvascular oxygenation (μHbO2) and perfusion (μflow) under physiological and hemorrhagic conditions.
Five dogs were repeatedly anesthetized.
All animals underwent each experimental protocol (randomized cross-over design): hypothermia (34°C), hypothermia during hemorrhage, normothermia, and normothermia during hemorrhage.
Microcirculatory and hemodynamic variables were recorded.
Systemic (DO2) and oral mucosal (μDO2) oxygen delivery were calculated.
Hypothermia increased oral μHbO2 with no effect on gastric μHbO2.
Hemorrhage reduced oral and gastric μHbO2 during normothermia (−36 ± 4% and −27 ± 7%); however, this effect was attenuated during additional hypothermia (−15 ± 5% and −11 ± 5%).
The improved μHbO2 might be based on an attenuated reduction in μflow during hemorrhage and additional hypothermia (−51 ± 21 aU) compared to hemorrhage and normothermia (−106 ± 19 aU).
μDO2 was accordingly attenuated under hypothermia during hemorrhage whereas DO2 did not change.
Thus, in this study hypothermia alone improves oral μHbO2 and attenuates the effects of hemorrhage on oral and gastric μHbO2.
This effect seems to be mediated by an increased μDO2 on the basis of increased μflow.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vollmer, Christian& Schwartges, Ingo& Swertz, Meike& Beck, Christopher& Bauer, Inge& Picker, Olaf. 2013. Hypothermia Improves Oral and Gastric Mucosal Microvascular Oxygenation during Hemorrhagic Shock in Dogs. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-483166
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vollmer, Christian…[et al.]. Hypothermia Improves Oral and Gastric Mucosal Microvascular Oxygenation during Hemorrhagic Shock in Dogs. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-483166
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vollmer, Christian& Schwartges, Ingo& Swertz, Meike& Beck, Christopher& Bauer, Inge& Picker, Olaf. Hypothermia Improves Oral and Gastric Mucosal Microvascular Oxygenation during Hemorrhagic Shock in Dogs. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-483166
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483166
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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