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Extreme Elevations in Blood Pressure and All-Cause Mortality in a Referred CKD Population : Results from the CRISIS Study
المؤلفون المشاركون
Chiu, Diana
Green, Darren
Kalra, Philip A.
Rainone, Francesco
Ritchie, James
Middleton, Rachel
O’Donoghue, Donal
Alderson, Helen
المصدر
International Journal of Hypertension
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Hypertension frequently complicates chronic kidney disease (CKD), with studies showing clinical benefit from blood pressure lowering.
Subgroups of patients with severe hypertension exist.
We aimed to identify patients with the greatest mortality risk from uncontrolled hypertension to define the prevalence and phenotype of patients who might benefit from adjunctive therapies.
1691 all-cause CKD patients from the CRISIS study were grouped by baseline blood pressure—target (<140/80 mmHg); elevated (140–190/80–100 mmHg); extreme (>190 and/or 100 mmHg).
Groups were well matched for age, eGFR, and comorbidities.
77 patients had extreme hypertension at recruitment but no increased mortality risk (HR 0.9, P=0.9) over a median follow-up period of 4.5 years.
The 1.2% of patients with extreme hypertension at recruitment and at 12-months had a significantly increased mortality risk (HR 4.3, P=0.01).
This association was not seen in patients with baseline extreme hypertension and improved 12-month blood pressures (HR 0.86, P=0.5).
Most CKD patients with extreme hypertension respond to pharmacological blood pressure control, reducing their risk for death.
Patients with extreme hypertension in whom blood pressure control cannot be achieved have an approximate prevalence of 1%.
These patients have an increased mortality risk and may be an appropriate group to consider for further therapies, including renal nerve ablation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ritchie, James& Rainone, Francesco& Green, Darren& Alderson, Helen& Chiu, Diana& Middleton, Rachel…[et al.]. 2013. Extreme Elevations in Blood Pressure and All-Cause Mortality in a Referred CKD Population : Results from the CRISIS Study. International Journal of Hypertension،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-483950
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ritchie, James…[et al.]. Extreme Elevations in Blood Pressure and All-Cause Mortality in a Referred CKD Population : Results from the CRISIS Study. International Journal of Hypertension No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-483950
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ritchie, James& Rainone, Francesco& Green, Darren& Alderson, Helen& Chiu, Diana& Middleton, Rachel…[et al.]. Extreme Elevations in Blood Pressure and All-Cause Mortality in a Referred CKD Population : Results from the CRISIS Study. International Journal of Hypertension. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-483950
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-483950
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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