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Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion
المؤلفون المشاركون
Zhang, Wei-Guo
Dong, Mei
Meng, Ke-Wei
Huang, Qing-Xian
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
Bile duct invasion (BDI) is a rare event in hepatocellular carcinoma (HCC).
The present study aimed at investigating clinical characteristics and surgical outcome of HCC patients with bile duct invasion.
Methods.
413 patients with HCC undergoing curative surgery were divided into two groups with (B+) and without BDI (B−).
BDI was further classified as central type (B1) and peripheral type (B2).
Survival was compared, and risk factors affecting prognosis were identified.
Results.
35 (8.5%) patients were diagnosed BDI.
Total bilirubin was significantly higher in B+ group than in B− group (P<0.001).
Multiple lesions and large nodules (>5 cm) were predominantly identified in B+ group (P<0.01, resp.).
Portal vein invasion was more frequently observed in B+ than in B− group (P=0.003).
Univariate and multivariate analyses identified central BDI as a significant factor affecting prognosis of HCC patients (risk 1.3, 95% CI 1.1–2.2, P=0.015).
The gross overall survival of patients in B+ was significantly worse than in B− (P=0.001), which, however, was not different between B2 and B− (P>0.05).
Conclusions.
Central but not peripheral BDI was associated with poorer prognosis of HCC patients.
Curative surgical resection of tumors and invaded bile duct supplies the only hope for long-term survival of patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meng, Ke-Wei& Dong, Mei& Zhang, Wei-Guo& Huang, Qing-Xian. 2014. Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484438
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meng, Ke-Wei…[et al.]. Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion. Gastroenterology Research and Practice No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-484438
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meng, Ke-Wei& Dong, Mei& Zhang, Wei-Guo& Huang, Qing-Xian. Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-484438
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-484438
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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