Lagochilascaris minor : Susceptibility and Resistance to Experimental Infection in Mice Is Independent of H-2a Haplotype and Correlates with the Immune Response in Immunized Animals
المؤلفون المشاركون
Hoffman Pfrimer, Irmtraut Araci
Vilarinho Tambourgi, Denise
Spadafora-Ferreira, Mônica
Fernandes, Luciana Caetano
Carvalhaes, Mara Silvia
Lino-Junior, Ruy de Souza
Pichiteli, Cássia Regina
المصدر
Journal of Parasitology Research
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-06-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Recently, we demonstrated that C57BL/6 mice are more susceptible to experimental lagochilascariosis than BALB/c mice.
To investigate the pattern of infection and the role of the genetic background on susceptibility to infection, we studied experimental lagochilascariosis in H-2a identical B10.A and A/J mice.
Infected B10.A mice had a lower survival ratio and more severe lesions in the lungs than did A/J mice.
Splenocytes of A/J mice immunized with the crude extract of the parasite showed increased proliferation and produced a higher level of interleukin 10 and interferon-γ in the presence of CE or concanavalin A when compared to B10.A mice.
This suggests that resistance of A/J mice may be due to less severe lesions in lungs and other organs and a better immune response to parasite antigens.
This paper provides evidence that major histocompatibility complex haplotype does not influence the survival to experimental infection with L.
minor.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Spadafora-Ferreira, Mônica& Fernandes, Luciana Caetano& Hoffman Pfrimer, Irmtraut Araci& Pichiteli, Cássia Regina& Vilarinho Tambourgi, Denise& Lino-Junior, Ruy de Souza…[et al.]. 2010. Lagochilascaris minor : Susceptibility and Resistance to Experimental Infection in Mice Is Independent of H-2a Haplotype and Correlates with the Immune Response in Immunized Animals. Journal of Parasitology Research،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-484948
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Spadafora-Ferreira, Mônica…[et al.]. Lagochilascaris minor : Susceptibility and Resistance to Experimental Infection in Mice Is Independent of H-2a Haplotype and Correlates with the Immune Response in Immunized Animals. Journal of Parasitology Research No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-484948
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Spadafora-Ferreira, Mônica& Fernandes, Luciana Caetano& Hoffman Pfrimer, Irmtraut Araci& Pichiteli, Cássia Regina& Vilarinho Tambourgi, Denise& Lino-Junior, Ruy de Souza…[et al.]. Lagochilascaris minor : Susceptibility and Resistance to Experimental Infection in Mice Is Independent of H-2a Haplotype and Correlates with the Immune Response in Immunized Animals. Journal of Parasitology Research. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-484948
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-484948
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر