MR Imaging of Prostate Cancer : Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology
المؤلفون المشاركون
Graessner, J.
Yamamura, J.
Adam, G.
Huland, H.
Wedegaetner, U.
Buchert, R.
Salomon, G.
Hohenstein, A.
Graefen, M.
المصدر
Radiology Research and Practice
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2010-07-20
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
To evaluate retrospectively the impact of diffusion weighted imaging (DWI) and (3D) hydrogen 1 (1H) MR-spectroscopy (MRS) on the detection of prostatic cancer in comparison to histological examinations.
Materials and Methods: 50 patients with suspicion of prostate cancer underwent a MRI examination at a 1.5T scanner.
The prostate was divided into sextants.
Regions of interest were placed in each sextant to evaluate the apparent diffusion coefficient (ADC)-values.
The results of the DWI as well as MRS were compared retrospectively with the findings of the histological examination.
Sensitivity and specificity of ADC and metabolic ratio (MET)—both separately and in combination—for identification of tumor tissue was computed for variable discrimination thresholds to evaluate its receiver operator characteristic (ROC).
An association between ADC, MET and Gleason score was tested by the non-parametric Spearman ρ-test.
Results.
The average ADC-value was 1.65±0.32mm2/s × 10-3 in normal tissue and 0.96±0.24 mm2/s × 10-3 in tumor tissue (mean ± 1 SD).
MET was 0.418±0.431 in normal tissue and 2.010 ±1.649 in tumor tissue.
The area under the ROC curve was 0.966 (95%-confidence interval 0.941–0.991) and 0.943 (0.918–0.968) for DWI and MRS, respectively.
There was a highly significant negative correlation between ADC-value and the Gleason score in the tumor-positive tissue probes (n=62, ρ=-0.405, P=.001).
MRS did not show a significant correlation with the Gleason score (ρ=0.117, P=.366).
By using both the DWI and MRS, the regression model provided sensitivity and specificity for detection of tumor of 91.9% and 98.3%, respectively.
Conclusion.
The results of our study showed that both DWI and MRS should be considered as an additional and complementary tool to the T2-weighted MRI for detecting prostate cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yamamura, J.& Salomon, G.& Buchert, R.& Hohenstein, A.& Graessner, J.& Huland, H.…[et al.]. 2010. MR Imaging of Prostate Cancer : Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology. Radiology Research and Practice،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-485430
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yamamura, J.…[et al.]. MR Imaging of Prostate Cancer : Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology. Radiology Research and Practice No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-485430
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yamamura, J.& Salomon, G.& Buchert, R.& Hohenstein, A.& Graessner, J.& Huland, H.…[et al.]. MR Imaging of Prostate Cancer : Diffusion Weighted Imaging and (3D) Hydrogen 1 (1H) MR Spectroscopy in Comparison with Histology. Radiology Research and Practice. 2010. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-485430
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-485430
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر