Transformation of Follicular Lymphoma to Double Hit B-Cell Lymphoma Causing Hypercalcemia in a 69-Year-Old Female : A Case Report and Review of the Literature
المؤلفون المشاركون
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Double hit B-cell lymphomas are rare tumors that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, mainly a t(14;18)(q32;q21) involving BCL2.
These tumors mostly occur in adults and carry a very poor prognosis.
Double hit lymphomas can occur de novo, or arise from transformation of follicular lymphoma.
We report a case of a 69-year-old female with abdominal distention and progressively worsening weakness over six months.
Patient presented with severe hypercalcemia and multiple intra-abdominal/pelvic masses.
Histopathology results of the abdominal mass were compatible with a double hit B-cell lymphoma.
However, bone marrow biopsy results showed a low grade follicular lymphoma, thus suggesting peripheral transformation of follicular lymphoma to double hit B-cell lymphoma.
Patient was transferred to a tertiary care center and was started on combination chemotherapy (EPOCH: doxorubicin, etoposide, vincristine, cyclophosphamide, and prednisone).
Our paper highlights not only transformation of follicular lymphoma to double hit B-cell lymphoma and the challenges encountered in diagnosing and treating these aggressive tumors, but also the association of new onset/worsening hypercalcemia in such patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kapur, Sakshi& Levin, Miles B.. 2014. Transformation of Follicular Lymphoma to Double Hit B-Cell Lymphoma Causing Hypercalcemia in a 69-Year-Old Female : A Case Report and Review of the Literature. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-485713
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kapur, Sakshi& Levin, Miles B.. Transformation of Follicular Lymphoma to Double Hit B-Cell Lymphoma Causing Hypercalcemia in a 69-Year-Old Female : A Case Report and Review of the Literature. Case Reports in Hematology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-485713
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kapur, Sakshi& Levin, Miles B.. Transformation of Follicular Lymphoma to Double Hit B-Cell Lymphoma Causing Hypercalcemia in a 69-Year-Old Female : A Case Report and Review of the Literature. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-485713
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-485713
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر