Experimental Models of Cryptococcosis

الملخص EN

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year.

Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types.

Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction.

Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.