Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents
المؤلفون المشاركون
Rathore, Mobeen H.
Bohannon, Beverly
Siberry, George K.
Barton, Theresa
Emmanuel, Patricia
Dominguez, Kenneth L.
Paul, Mary E.
Frederick, Toni
Wheeling, Travis
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Methicillin-resistant Staphylococcus aureus (MRSA) infection incidence has increased in healthy US children.
Our objective was to evaluate MRSA incidence and correlates in HIV-infected youth.
Methods.
The CDC-sponsored LEGACY study is a US multicenter chart abstraction study of HIV-infected youth.
We identified MRSA infections among participants with ≥1 visit during 2006.
We used bivariate and multivariable analyses to compare sociodemographic and HIV clinical factors between MRSA cases and noncases.
Results.
Fourteen MRSA infections (1 invasive, 12 soft tissue, 1 indeterminate) occurred among 1,813 subjects (11.1 infections/1,000 patient-years (PY), 95% CI: 11.06–11.14).
Most (86%) isolates were clindamycin susceptible.
Compared with noncases, MRSA cases were more likely older (17 versus 14 years), black (100% versus 69%), behaviorally HIV infected (43% versus 17%), and in Maryland (43% versus 7%) and had viral loads (VL) >1000 copies/mL (86% versus 51%) and lower mean CD4% (18% versus 27%) (all P<0.05).
In multivariate analysis, independent risk factors were Maryland care site (adjusted odds ratio (aOR) = 9.0), VL >1000 copies/mL (aOR = 5.9), and black race (aOR undefined).
Conclusions.
MRSA occurred at a rate of 11.1 infections/1,000 PY in HIV-infected youth but invasive disease was uncommon.
Geographic location, black race, and increased VL, but not immunosuppression, were independently associated with MRSA risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Siberry, George K.& Frederick, Toni& Emmanuel, Patricia& Paul, Mary E.& Bohannon, Beverly& Wheeling, Travis…[et al.]. 2012. Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486334
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Siberry, George K.…[et al.]. Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents. AIDS Research and Treatment No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-486334
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Siberry, George K.& Frederick, Toni& Emmanuel, Patricia& Paul, Mary E.& Bohannon, Beverly& Wheeling, Travis…[et al.]. Methicillin-Resistant Staphylococcus aureus Infections in Human Immunodeficiency Virus-Infected Children and Adolescents. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-486334
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486334
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر