Vitamin D Deficiency and Insufficiency in Obese Children and Adolescents and Its Relationship with Insulin Resistance
المؤلفون المشاركون
Özgen, İlker Tolga
Öktem, Faruk
Gönüllü, Erdem
Cindemir, Ergül
Torun, Emel
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-03-27
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objectives.
We aimed to determine the relationship between insulin resistance and serum 25-hydroxyvitamin D (25-OHD) levels in obese children and their nonobese peers.
Materials and Methods.
Included in the study group were 188 obese children (aged 9–15 years), and 68 age- and gender-matched healthy children of normal weight as control group.
Anthropomorphic data were collected on patients and fasting serum glucose, insulin, serum lipids, alanine aminotransaminase (ALT) and 25-OHD were measured.
The homeostatic model assessment of insulin resistance (HOMA-IR) was calculated in both groups.
Results.
The levels of 25-OHD in the obese group were significantly lower than those of the nonobese (P=0.002).
HOMA-IR, triglycerides, low-density lipoprotein, and ALT levels in the obese group were significantly higher than values of control group (P<0.001 and P=0.002, resp.).
In the obese group, vitamin D deficiency, insufficiency, and sufficiency (25-OHD < 10 ng/dl, < 20, >10 ng/dl; > 20 ng/dl, resp.) were not correlated with HOMA-IR (r:−0.008, P=0.935).
HOMA-IR was negatively correlated with BMI, BMI SDS, and BMI%, and triglycerides, low-density lipoprotein, and ALT levels (P<0.001).
Conclusion.
The insulin resistance of the obese subjects who were vitamin D deficient and insufficient did not statistically differ from those with vitamin D sufficiency.
Low 25-hydroxyvitamin D levels were not related with higher insulin resistance in obese children and adolescents.
In obese subjects, insulin resistance was affected more from BMI, BMI SDS, and BMI% than from 25-hydroxyvitamin D levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Torun, Emel& Gönüllü, Erdem& Özgen, İlker Tolga& Cindemir, Ergül& Öktem, Faruk. 2013. Vitamin D Deficiency and Insufficiency in Obese Children and Adolescents and Its Relationship with Insulin Resistance. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-486692
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Torun, Emel…[et al.]. Vitamin D Deficiency and Insufficiency in Obese Children and Adolescents and Its Relationship with Insulin Resistance. International Journal of Endocrinology No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-486692
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Torun, Emel& Gönüllü, Erdem& Özgen, İlker Tolga& Cindemir, Ergül& Öktem, Faruk. Vitamin D Deficiency and Insufficiency in Obese Children and Adolescents and Its Relationship with Insulin Resistance. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-486692
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486692
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر