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Effects of Hypertension and Exercise on Cardiac Proteome Remodelling
المؤلفون المشاركون
Petriz, Bernardo A.
Franco, Octavio L.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-27
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Left ventricle hypertrophy is a common outcome of pressure overload stimulus closely associated with hypertension.
This process is triggered by adverse molecular signalling, gene expression, and proteome alteration.
Proteomic research has revealed that several molecular targets are associated with pathologic cardiac hypertrophy, including angiotensin II, endothelin-1 and isoproterenol.
Several metabolic, contractile, and stress-related proteins are shown to be altered in cardiac hypertrophy derived by hypertension.
On the other hand, exercise is a nonpharmacologic agent used for hypertension treatment, where cardiac hypertrophy induced by exercise training is characterized by improvement in cardiac function and resistance against ischemic insult.
Despite the scarcity of proteomic research performed with exercise, healthy and pathologic heart proteomes are shown to be modulated in a completely different way.
Hence, the altered proteome induced by exercise is mostly associated with cardioprotective aspects such as contractile and metabolic improvement and physiologic cardiac hypertrophy.
The present review, therefore, describes relevant studies involving the molecular characteristics and alterations from hypertensive-induced and exercise-induced hypertrophy, as well as the main proteomic research performed in this field.
Furthermore, proteomic research into the effect of hypertension on other target-demerged organs is examined.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Petriz, Bernardo A.& Franco, Octavio L.. 2014. Effects of Hypertension and Exercise on Cardiac Proteome Remodelling. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-486823
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Petriz, Bernardo A.& Franco, Octavio L.. Effects of Hypertension and Exercise on Cardiac Proteome Remodelling. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-486823
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Petriz, Bernardo A.& Franco, Octavio L.. Effects of Hypertension and Exercise on Cardiac Proteome Remodelling. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-486823
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486823
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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