The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma
المؤلفون المشاركون
Kovacs, Joseph A.
Greenspan, John S.
Iadarola, Michael J.
Rhodes, Craig S.
Burbelo, Peter D.
Bayat, Ahmad
De Souza, Yvonne
Wagner, Jason
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-08
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Although HIV-positive patients are at higher risk for developing a variety of infection-related cancers, the prevalence of infections with the seven known cancer-associated viruses has not been studied.
Luciferase immunoprecipitation systems were used to evaluate antiviral antibodies in four 23-person groups: healthy blood donors and HIV-infected patients with oral hairy leukoplakia (OLP), Kaposi's sarcoma (KS), or non-Hodgkin lymphoma (NHL).
Antibody profiling revealed that all HIV-positive individuals were strongly seropositive for anti-gp41 and antireverse transcriptase antibodies.
However, anti-p24 HIV antibody levels were highly variable and some OLP and KS patients demonstrated weak or negative responses.
Profiling two EBV antigens revealed no statistical difference in antibody levels among the three HIV-infected groups.
A high frequency of KSHV infection was detected in HIV patients including 100% of KS, 78% of OLP, and 57% of NHL patients.
Most HIV-infected subjects (84%) showed anti-HBV core antibodies, but only a few showed antibodies against HCV.
MCV seropositivity was also common (94%) in the HIV-infected individuals and KS patients showed statistically higher antibody levels compared to the OLP and NHL patients.
Overall, 68% of the HIV-infected patients showed seropositivity with at least four cancer-associated viruses.
Antibody profiles against these and other infectious agents could be useful for enhancing the clinical management of HIV patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Burbelo, Peter D.& Kovacs, Joseph A.& Wagner, Jason& Bayat, Ahmad& Rhodes, Craig S.& De Souza, Yvonne…[et al.]. 2012. The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma. AIDS Research and Treatment،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-486861
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Burbelo, Peter D.…[et al.]. The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma. AIDS Research and Treatment No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-486861
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Burbelo, Peter D.& Kovacs, Joseph A.& Wagner, Jason& Bayat, Ahmad& Rhodes, Craig S.& De Souza, Yvonne…[et al.]. The Cancer-Associated Virus Landscape in HIV Patients with Oral Hairy Leukoplakia, Kaposi's Sarcoma, and Non-Hodgkin Lymphoma. AIDS Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-486861
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-486861
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر