Analysis of Serum and Urinal Copper and Zinc in Chinese Northeast Population with the Prediabetes or Diabetes with and without Complications

المؤلفون المشاركون

Cai, Lu
Liu, Gilbert
Xu, Jiancheng
Tan, Yi
Zhou, Qi

المصدر

Oxidative Medicine and Cellular Longevity

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-09-22

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء

الملخص EN

This study investigated the association of copper and zinc levels in the serum or urine of patients living in northeast China, with either prediabetes or diabetes.

From January 2010 to October 2011, patients with type 1 diabetes (T1D, n=25), type 2 diabetes (T2D, n=137), impaired fasting glucose (IFG, n = 12) or impaired glucose tolerance (IGT, n=15), and age/gender matched controls (n=50) were enrolled.

In the T2D group, there were 24 patients with nephropathy, 34 with retinopathy, and 50 with peripheral neuropathy.

Serum copper levels were significantly higher in IFG, IGT, and T2D groups.

Serum zinc level was dramatically lower, and urinary zinc level was significantly higher in both T1D and T2D subjects compared with controls.

The serum zinc/copper ratio was significantly lower in all the patients with IFG, ITG, T1D, and T2D.

The serum copper level was positively associated with HbA1c in T2D subjects.

Simvastatin treatment in T2D patients had no significant effect on serum and urinary copper and zinc.

These results suggest the need for further studies of the potential impact of the imbalanced serum copper and zinc levels on metabolic syndrome, diabetes, and diabetic complications.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Xu, Jiancheng& Zhou, Qi& Liu, Gilbert& Tan, Yi& Cai, Lu. 2013. Analysis of Serum and Urinal Copper and Zinc in Chinese Northeast Population with the Prediabetes or Diabetes with and without Complications. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-486939

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Xu, Jiancheng…[et al.]. Analysis of Serum and Urinal Copper and Zinc in Chinese Northeast Population with the Prediabetes or Diabetes with and without Complications. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-486939

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Xu, Jiancheng& Zhou, Qi& Liu, Gilbert& Tan, Yi& Cai, Lu. Analysis of Serum and Urinal Copper and Zinc in Chinese Northeast Population with the Prediabetes or Diabetes with and without Complications. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-486939

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-486939