Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems
المؤلفون المشاركون
Siddiqi, Nikhat Jamal
Sharma, Bechan
Singh, Shweta
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-26، 26ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-12
دولة النشر
مصر
عدد الصفحات
26
التخصصات الرئيسية
الملخص EN
Several workers have extensively worked out the metal induced toxicity and have reported the toxic and carcinogenic effects of metals in human and animals.
It is well known that these metals play a crucial role in facilitating normal biological functions of cells as well.
One of the major mechanisms associated with heavy metal toxicity has been attributed to generation of reactive oxygen and nitrogen species, which develops imbalance between the prooxidant elements and the antioxidants (reducing elements) in the body.
In this process, a shift to the former is termed as oxidative stress.
The oxidative stress mediated toxicity of heavy metals involves damage primarily to liver (hepatotoxicity), central nervous system (neurotoxicity), DNA (genotoxicity), and kidney (nephrotoxicity) in animals and humans.
Heavy metals are reported to impact signaling cascade and associated factors leading to apoptosis.
The present review illustrates an account of the current knowledge about the effects of heavy metals (mainly arsenic, lead, mercury, and cadmium) induced oxidative stress as well as the possible remedies of metal(s) toxicity through natural/synthetic antioxidants, which may render their effects by reducing the concentration of toxic metal(s).
This paper primarily concerns the clinicopathological and biomedical implications of heavy metals induced oxidative stress and their toxicity management in mammals.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sharma, Bechan& Singh, Shweta& Siddiqi, Nikhat Jamal. 2014. Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems. BioMed Research International،Vol. 2014, no. 2014, pp.1-26.
https://search.emarefa.net/detail/BIM-487448
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sharma, Bechan…[et al.]. Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems. BioMed Research International No. 2014 (2014), pp.1-26.
https://search.emarefa.net/detail/BIM-487448
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sharma, Bechan& Singh, Shweta& Siddiqi, Nikhat Jamal. Biomedical Implications of Heavy Metals Induced Imbalances in Redox Systems. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-26.
https://search.emarefa.net/detail/BIM-487448
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-487448
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر