Repeated Muscle Injury as a Presumptive Trigger for Chronic Masticatory Muscle Pain
المؤلفون المشاركون
Lovering, Richard M.
Dessem, Dean
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-06-12
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
skeletal muscles sustain a significant loss of maximal contractile force after injury, but terminally damaged fibers can eventually be replaced by the growth of new muscle (regeneration), with full restoration of contractile force over time.
After a second injury, limb muscles exhibit a smaller reduction in maximal force and reduced inflammation compared with that after the initial injury (i.e., repeated bout effect).
In contrast, masticatory muscles exhibit diminished regeneration and persistent fibrosis, after a single injury; following a second injury, plasma extravasation is greater than after a single injury and maximal force is decreased more than after the initial injury.
Thus, masticatory muscles do not exhibit a repeated bout effect and are instead increasingly damaged by repeated injury.
We propose that the impaired ability of masticatory muscles to regenerate contributes to chronic muscle pain by leading to an accumulation of tissue damage, fibrosis, and a persistent elevation and prolonged membrane translocation of nociceptive channels such as P2X3 as well as enhanced expression of neuropeptides including CGRP within primary afferent neurons.
These transformations prime primary afferent neurons for enhanced responsiveness upon subsequent injury thus triggering and/or exacerbating chronic muscle pain.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dessem, Dean& Lovering, Richard M.. 2011. Repeated Muscle Injury as a Presumptive Trigger for Chronic Masticatory Muscle Pain. Pain Research and Treatment،Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-487983
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dessem, Dean& Lovering, Richard M.. Repeated Muscle Injury as a Presumptive Trigger for Chronic Masticatory Muscle Pain. Pain Research and Treatment No. 2011 (2011), pp.1-13.
https://search.emarefa.net/detail/BIM-487983
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dessem, Dean& Lovering, Richard M.. Repeated Muscle Injury as a Presumptive Trigger for Chronic Masticatory Muscle Pain. Pain Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-13.
https://search.emarefa.net/detail/BIM-487983
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-487983
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر