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Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay
المؤلفون المشاركون
Anders, Margarita
Goldaracena, Nicolás
Quiñonez, Emilio
Koo, Lucio
Orozco, Federico
Mastai, Ricardo C.
Méndez, Patricio
McCormack, Lucas
Devetach, Gustavo
Jeanes, Carlos
Comignani, Pablo D.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Significant amounts of red blood cells (RBCs) transfusions are associated with poor outcome after liver transplantation (LT).
We report our series of LT without perioperative RBC (P-RBC) transfusions to evaluate its influence on early and long-term outcomes following LT.
Methods.
A consecutive series of LT between 2006 and 2011 was analyzed.
P-RBC transfusion was defined as one or more RBC units administrated during or ≤48 hours after LT.
We divided the cohort in “No-Transfusion” and “Yes-Transfusion.” Preoperative status, graft quality, and intra- and postoperative variables were compared to assess P-RBC transfusion risk factors and postoperative outcome.
Results.
LT was performed in 127 patients (“No-Transfusion” = 39 versus “Yes-Transfusion” = 88).
While median MELD was significantly higher in Yes-Transfusion (11 versus 21; P=0.0001) group, platelet count, prothrombin time, and hemoglobin were significantly lower.
On multivariate analysis, the unique independent risk factor associated with P-RBC transfusions was preoperative hemoglobin (P<0.001).
Incidence of postoperative bacterial infections (10 versus 27%; P=0.03), median ICU (2 versus 3 days; P=0.03), and hospital stay (7.5 versus 9 days; P=0.01) were negatively influenced by P-RBC transfusions.
However, 30-day mortality (10 versus 15%) and one- (86 versus 70%) and 3-year (77 versus 66%) survival were equivalent in both groups.
Conclusions.
Recipient MELD score was not a predictive factor for P-RBC transfusion.
Patients requiring P-RBC transfusions had worse postoperative outcome.
Therefore, maximum efforts must be focused on improving hemoglobin levels during waiting list time to prevent using P-RBC in LT recipients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Goldaracena, Nicolás& Méndez, Patricio& Quiñonez, Emilio& Devetach, Gustavo& Koo, Lucio& Jeanes, Carlos…[et al.]. 2013. Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay. Journal of Transplantation،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-488107
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Goldaracena, Nicolás…[et al.]. Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay. Journal of Transplantation No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-488107
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Goldaracena, Nicolás& Méndez, Patricio& Quiñonez, Emilio& Devetach, Gustavo& Koo, Lucio& Jeanes, Carlos…[et al.]. Liver Transplantation without Perioperative Transfusions Single-Center Experience Showing Better Early Outcome and Shorter Hospital Stay. Journal of Transplantation. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-488107
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488107
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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