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Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites
المؤلفون المشاركون
Cavalcanti Zonari, Alessandra Arcoverde
Ozyegin, Lutfiye S.
Graça, Manuel Pedro F.
Valério, Patrícia
Oktar, Faik N.
de Goes, Alfredo Miranda
Leite, Maria F.
Shainberg, Ana Paula M.
المصدر
Advances in Materials Science and Engineering
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-04-24
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
العلوم الهندسية و تكنولوجيا المعلومات
الملخص EN
The biocompatibility and bioactivity properties of hydroxyapatites (HAs) modified through lithium addition were investigated.
Hydroxyapatites obtained from bovine bone were mixed with lithium carbonate (Li), in the proportions of 0.25, 0.50, 1.00, and 2.00% wt, and sintered at 900°, 1000°, 1100°, 1200°, and 1300°C, creating LiHA samples.
The osteoblast culture behavior was assessed in the presence of these LiHA compositions.
The cellular interactions were analyzed by evaluating the viability and cellular proliferation, ALP production and collagen secretion.
The cytotoxic potential was investigated through measurement of apoptosis and necrosis induction.
The process of cellular attachment in the presence of the product of dissolution of LiHA, was evaluated trough fluorescence analysis.
The physical characteristics of these materials and their cellular interactions were examined with SEM and EDS.
The results of this study indicate that the LiHA ceramics are biocompatible and have variable bioactivities, which can be tailored by different combinations of the concentration of lithium carbonate and the sintering temperature.
Our findings suggest that LiHA 0.25% wt, sintered at 1300°C, combines the necessary physical and structural qualities with favorable biocompatibility characteristics, achieving a bioactivity that seems to be adequate for use as a bone implant material.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shainberg, Ana Paula M.& Valério, Patrícia& Cavalcanti Zonari, Alessandra Arcoverde& Oktar, Faik N.& Ozyegin, Lutfiye S.& Graça, Manuel Pedro F.…[et al.]. 2012. Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites. Advances in Materials Science and Engineering،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-488234
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shainberg, Ana Paula M.…[et al.]. Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites. Advances in Materials Science and Engineering No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-488234
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shainberg, Ana Paula M.& Valério, Patrícia& Cavalcanti Zonari, Alessandra Arcoverde& Oktar, Faik N.& Ozyegin, Lutfiye S.& Graça, Manuel Pedro F.…[et al.]. Attachment and Proliferation of Osteoblasts on Lithium-Hydroxyapatite Composites. Advances in Materials Science and Engineering. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-488234
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488234
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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