Adherence and Persistence with Once-Daily Teriparatide in Japan : A Retrospective, Prescription Database, Cohort Study

المؤلفون المشاركون

Graham-Clarke, Peita
Burge, Russel T.
Flynn, Jennifer A.
Sugihara, Tomoko
Nojiri, Shuko
Faries, Douglas E.
Sato, Masayo
Tanaka, Ikuko

المصدر

Journal of Osteoporosis

العدد

المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2013-12-12

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Adherence and persistence with osteoporosis treatments are essential for reducing fracture risk.

Once-daily teriparatide is available in Japan for treating osteoporosis in patients with a high risk of fracture.

The study objective was to describe real-world adherence and persistence with once-daily teriparatide 20 μg during the first year of treatment for patients who started treatment during the first eight months of availability in Japan.

This prescription database study involved patients with an index date (first claim) between October 2010 and May 2011, a preindex period ≥6 months, and a postindex period ≥12 months and who were aged >45 years.

Adherence (medication possession ratio (MPR)) and persistence (time from the start of treatment to discontinuation; a 60-day gap in supply) were calculated.

A total of 287 patients started treatment during the specified time period; 123 (42.9%) were eligible for inclusion.

Overall mean (standard deviation) adherence was 0.702 (0.366), with 61.0% of patients having high adherence (MPR > 0.8).

The percentage of patients remaining on treatment was 65.9% at 180 days and 61.0% at 365 days.

Our findings suggest that real-world adherence and persistence with once-daily teriparatide in Japan are similar to that with once-daily teriparatide in other countries and with other osteoporosis medications.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Tanaka, Ikuko& Sato, Masayo& Sugihara, Tomoko& Faries, Douglas E.& Nojiri, Shuko& Graham-Clarke, Peita…[et al.]. 2013. Adherence and Persistence with Once-Daily Teriparatide in Japan : A Retrospective, Prescription Database, Cohort Study. Journal of Osteoporosis،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-488605

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Tanaka, Ikuko…[et al.]. Adherence and Persistence with Once-Daily Teriparatide in Japan : A Retrospective, Prescription Database, Cohort Study. Journal of Osteoporosis No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-488605

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Tanaka, Ikuko& Sato, Masayo& Sugihara, Tomoko& Faries, Douglas E.& Nojiri, Shuko& Graham-Clarke, Peita…[et al.]. Adherence and Persistence with Once-Daily Teriparatide in Japan : A Retrospective, Prescription Database, Cohort Study. Journal of Osteoporosis. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-488605

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-488605