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The Evaluation of Diastolic Dysfunction with Tissue Doppler Echocardiography in Women with Subclinical Hypothyroidism and the Effect of L-Thyroxine Treatment on Diastolic Dysfunction : A Pilot Study
المؤلفون المشاركون
Cesur, Mustafa
Karaahmetoglu, Selma
Erkan, Gulbanu
Cemri, Mustafa
Cengel, Atiye
Erkan, Aycan Fahri
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-08-08
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Subclinical hypothyroidism (SH) predominantly affects women.
The necessity of treatment in SH is controversial.
Objective.
We aimed to investigate the response of diastolic dysfunction to thyroid hormone replacement therapy (THRT) in women.
Methods and Results.
Twenty-two female subjects with SH and 20 euthyroid female controls were enrolled.
Baseline and follow-up biochemical, hormonal, and echocardiographic evaluations were performed.
Repeat echocardiograms were performed three months after the achievement of a euthyroid status with THRT.
Mean baseline myocardial performance index (MPI) was 0.27±0.08 in the SH group, and 0.22±0.06 in the control group (P=0.03).
MPI did not change significantly after THRT.
Pulsed-wave Doppler findings were not different among the groups.
However, tissue Doppler-derived mitral annular E’ velocities were significantly lower in the SH group.
A moderate but significant improvement was observed in E’ velocities after THRT (13.2±3.87 versus 14.53±2.75, P=0.04).
We also observed left ventricular concentric remodeling in SH patients which was reversible with THRT.
Conclusions.
Tissue Doppler echocardiography may be a useful tool for monitoring the response of diastolic dysfunction to thyroid hormone replacement therapy in patients with SH.
Our findings suggest that THRT may reverse diastolic dysfunction in women with SH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Erkan, Gulbanu& Erkan, Aycan Fahri& Cemri, Mustafa& Karaahmetoglu, Selma& Cesur, Mustafa& Cengel, Atiye. 2011. The Evaluation of Diastolic Dysfunction with Tissue Doppler Echocardiography in Women with Subclinical Hypothyroidism and the Effect of L-Thyroxine Treatment on Diastolic Dysfunction : A Pilot Study. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-488618
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Erkan, Gulbanu…[et al.]. The Evaluation of Diastolic Dysfunction with Tissue Doppler Echocardiography in Women with Subclinical Hypothyroidism and the Effect of L-Thyroxine Treatment on Diastolic Dysfunction : A Pilot Study. Journal of Thyroid Research No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-488618
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Erkan, Gulbanu& Erkan, Aycan Fahri& Cemri, Mustafa& Karaahmetoglu, Selma& Cesur, Mustafa& Cengel, Atiye. The Evaluation of Diastolic Dysfunction with Tissue Doppler Echocardiography in Women with Subclinical Hypothyroidism and the Effect of L-Thyroxine Treatment on Diastolic Dysfunction : A Pilot Study. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-488618
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488618
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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