![](/images/graphics-bg.png)
Clinical and Immunological Analysis of Cutaneous Leishmaniasis before and after Different Treatments
المؤلفون المشاركون
O'Daly, José A.
Rodríguez, María B.
Gleason, Joe
Spinetti, Humberto M.
المصدر
Journal of Parasitology Research
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-13
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Amastigotes from L.
(L.)amazonensis (La), L.
(L.)venezuelensis (Lv), L.
(V.)brasiliensis (Lb), and L.
(L.)chagasi (Lch) were cultured in a free cells liquid culture medium.
Patients (n=87) from a cutaneous leishmaniasis (CL) hyperendemic region receiving different treatments were followed up from January 1994 to August 2000.
Time for remission of lesions were spontaneous remission (SR) 7 weeks; Glucantime (Glu) chemotherapy 9 weeks; immunotherapy with La, Lv, Lb, and Lch amastigotes Tosyl-Lysil Chloromethyl-ketone (TLCK) treated and Nonidet P-40(NP-40) extracted (VT) 7 weeks.
Delayed type hypersensitivity (DTH) response with leishmanine intradermic reaction (IDR) was higher in CL patients than healthy controls (P<0.05) and increased in active secondary versus primary infection (P<0.001) with diagnostic value 1.74 for active infection and 1.81 postclinical remission.
Antibodies to amastigotes characterized by Enzyme Linked Immunosorbent Assay (ELISA) decreased in sera postclinical remission versus active infections (P<0.001), with a diagnostic value from 1.50 to 1.84.
Immunoblottings antigenic bands frequency as well as Integral Optical Density (IOD) Area Densitometry decreased with sera from SR, after Glu or VT treatments in CL volunteers.
Intracellular parasitism is due to normal antibodies recognizing parasite antigens after inoculation by vector.
VT vaccine induced mainly cellular immunity, for remission of lesions and protection from CL infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
O'Daly, José A.& Spinetti, Humberto M.& Gleason, Joe& Rodríguez, María B.. 2013. Clinical and Immunological Analysis of Cutaneous Leishmaniasis before and after Different Treatments. Journal of Parasitology Research،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-488759
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
O'Daly, José A.…[et al.]. Clinical and Immunological Analysis of Cutaneous Leishmaniasis before and after Different Treatments. Journal of Parasitology Research No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-488759
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
O'Daly, José A.& Spinetti, Humberto M.& Gleason, Joe& Rodríguez, María B.. Clinical and Immunological Analysis of Cutaneous Leishmaniasis before and after Different Treatments. Journal of Parasitology Research. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-488759
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-488759
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)