Refractory Gout Attack

الملخص EN

Refractory gout attack is an uncommon problem, since gout flares are usually self-limited.

This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi.

We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera levels.

In order to manage this problem, we reviewed gout pathophysiology and developed a therapeutic solution based on benzbromarone pharmacokinetics.

We also review herein new options for gout treatment that could be used in similar cases.