Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years

الملخص EN

Little is known on long-term outcomes in kidney transplantation.

This study evaluated changes and predictors of generic and transplantation-specific health-related quality of life (HQoL) over six years in N=102 kidney transplant survivors using the Short-form Health Survey-36 and the Transplant Effects questionnaire.

Mixed models analysis was used to determine long-term outcomes.

Emotional HQoL improved over time: Mental Component score, Mental Health, Energy (Ps=.000).

Physical HQoL deteriorated: Physical Component Score (P=.001), Pain (P=.002).

LRD transplant recipients had greater decline in physical functioning (P=.003) and PCS (P=.000) compared to cadaver recipients.

Worry about the transplant (P=.036) and feelings of responsibility (P=.008) increased significantly over time.

Worry about the transplant and perceived ability to work predicted 12.7% and 31.1% in variance in MCS and PCS, respectively.

Efforts should be made to maintain HQoL and emotional outcomes with ongoing monitoring and support programs throughout the course of posttransplant care.