Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin
المؤلفون المشاركون
Chiu, Yung-jia
Peng, Wen-Huang
Lin, Ying-Chih
Liu, Chia-Yu
Huang, Tai-Hung
Lu, Tsung-Chun
Liao, Jung-Chun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-02-14
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Pogostemon cablin (PC) is a herbal medicine traditionally applied to treat not only common cold, nausea and diarrhea but also headache and fever.
The aim of this study was to investigate the analgesic and anti-inflammatory properties of standardized PC methanol extract (PCMeOH) in vivo.
Investigations were performed in mice with two analgesic models.
One was acetic acid-induced writhing response and the other formalin-induced paw licking.
The anti-inflammatory effect was tested by λ-carrageenan (Carr)-induced mice paw edema.
These analgesic experimental results indicated that PCMeOH (1.0 g/kg) decreased the acetic acid-induced writhing responses and PCMeOH (0.5 and 1.0 g/kg) decreased the licking time in the second phase of the formalin test.
Moreover, Carr-induced paw edema inflammation was significantly reduced in a dose-dependent manner when PCMeOH (0.5 and 1.0 g/kg) was administered 3 and 4 h after the Carr injection.
Mechanistic studies showed that PCMeOH decreased the levels of malondialdehyde in the edema paw by increasing the activities of anti-oxidant enzymes, such as superoxide dismutase, glutathione peroxidase and glutathione reductase, in the liver and decreasing the cyclooxygenase 2 and tumor necrosis factor-α activities in the edema paw.
This study has demonstrated the analgesic and anti-inflammatory effects of PCMeOH, thus verifying its popular use in traditional medicine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Tsung-Chun& Liao, Jung-Chun& Huang, Tai-Hung& Lin, Ying-Chih& Liu, Chia-Yu& Chiu, Yung-jia…[et al.]. 2011. Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-489229
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Tsung-Chun…[et al.]. Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-489229
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Tsung-Chun& Liao, Jung-Chun& Huang, Tai-Hung& Lin, Ying-Chih& Liu, Chia-Yu& Chiu, Yung-jia…[et al.]. Analgesic and Anti-Inflammatory Activities of the Methanol Extract from Pogostemon cablin. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-489229
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-489229
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر