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Effects of Single Exposure of Sodium Fluoride on Lipid Peroxidation and Antioxidant Enzymes in Salivary Glands of Rats
المؤلفون المشاركون
Ganzerla, Emily
Yamaguti, Paula Mochidome
Souza, Douglas Nesadal
Nogueira, Fernando Neves
Simões, Alyne
Nicolau, José
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Many studies suggest that fluoride exposure can inhibit the activity of various enzymes and can generate free radicals, which interfere with antioxidant defence mechanisms in living systems.
To further the understanding of this issue, this present study examined the effects of low-dose fluoride treatment on the activity of enzymatic antioxidant superoxide dismutase (SOD) and catalase (CAT), as well as the levels of lipid peroxidation (LPO) in the parotid (PA) and submandibular (SM) salivary glands of rats.
Rats were injected with a single dose of sodium fluoride (NaF) (15 mg F−/kg b.w.) then euthanized at various time intervals up to 24 hours (h) following exposure.
NaF exposure did not cause significant differences in SOD or CAT activity or LPO levels in PA glands compared to control.
Conversely, SM glands presented increased SOD activity after 3 h and decreased SOD activity after 1, 12, and 24 h, while LPO was increased after 6, 12, and 24 h of the NaF injection.
There were no significant differences in the CAT activity in the groups studied.
Our results demonstrated that NaF intoxication caused oxidative stress in salivary glands few hours after administration.
These changes were more pronounced in SM than in PA gland.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yamaguti, Paula Mochidome& Simões, Alyne& Ganzerla, Emily& Souza, Douglas Nesadal& Nogueira, Fernando Neves& Nicolau, José. 2013. Effects of Single Exposure of Sodium Fluoride on Lipid Peroxidation and Antioxidant Enzymes in Salivary Glands of Rats. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-489516
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yamaguti, Paula Mochidome…[et al.]. Effects of Single Exposure of Sodium Fluoride on Lipid Peroxidation and Antioxidant Enzymes in Salivary Glands of Rats. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-489516
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yamaguti, Paula Mochidome& Simões, Alyne& Ganzerla, Emily& Souza, Douglas Nesadal& Nogueira, Fernando Neves& Nicolau, José. Effects of Single Exposure of Sodium Fluoride on Lipid Peroxidation and Antioxidant Enzymes in Salivary Glands of Rats. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-489516
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-489516
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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