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Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES) : Case Report
المؤلفون المشاركون
Barni, S.
Novembre, E.
Cianferoni, A.
Pucci, N.
Mori, F.
de Martino, M.
المصدر
Clinical and Developmental Immunology
العدد
المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2009-11-17
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy characterized by severe vomiting, diarrhea, and often failure to thrive in infants.
Symptoms typically resolve after the triggering food-derived protein is removed from the diet and recur within few hours after the re-exposure to the causal protein.
The diagnosis is based on clinical symptoms and a positive food challenge.
In this study, we report a case of FPIES to rice in an 8-month-old boy.
We performed a double-blind placebo-controlled food challenge (DBPCFC) to rice and we measured the intracellular T cell expression of interleukin-4 (IL-4); IL-10, and interferon γ (IFN-γ) pre-and post-challenge during an acute FPIES reaction and when tolerance to rice had been achieved.
For the first time we describe an increase in T cell IL-4 and decrease in IFN-γ expression after a positive challenge with rice (i.e.
rice triggered a FPIES attack) and an increase in T cell IL-10 expression after rice challenge 6 months later after a negative challenge (i.e., the child had acquired tolerance to rice) in an 8 month old with documented FPIES to rice.
A Th2 activation associated with high IL-4 levels may contribute to the pathophysiology of the disease.
On the other hand, T cell-derived IL-10 may play a role in the acquisition of immunotolerance by regulating the Th1 and Th2 responses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mori, F.& Barni, S.& Cianferoni, A.& Pucci, N.& de Martino, M.& Novembre, E.. 2009. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES) : Case Report. Clinical and Developmental Immunology،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-489872
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mori, F.…[et al.]. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES) : Case Report. Clinical and Developmental Immunology No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-489872
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mori, F.& Barni, S.& Cianferoni, A.& Pucci, N.& de Martino, M.& Novembre, E.. Cytokine Expression in CD3+ Cells in an Infant with Food Protein-Induced Enterocolitis Syndrome (FPIES) : Case Report. Clinical and Developmental Immunology. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-489872
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-489872
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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