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Treatment of Vertigo : A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine
المؤلفون المشاركون
Hoerr, Robert
Sokolova, Larysa
Mishchenko, Tamara
المصدر
International Journal of Otolaryngology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-25
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
A multicenter clinical trial was performed to compare the efficacy and safety of Ginkgo biloba extract EGb 761 and betahistine at recommended doses in patients with vertigo.
One hundred and sixty patients (mean age 58 years) were randomly assigned to double-blind treatment with EGb 761 (240 mg per day) or betahistine (32 mg per day) for 12 weeks.
An 11-point numeric analogue scale, the Vertigo Symptom Scale—short form, the Clinical Global Impression Scales and the Sheehan Disability Scale were used as outcome measures.
Both treatment groups were comparable at baseline and improved in all outcome measures during the course of treatment.
There was no significant intergroup difference with regard to changes in any outcome measure.
Numerically, improvements of patients receiving EGb 761 were slightly more pronounced on all scales.
Clinical global impression was rated “very much improved” or “much improved” in 79% of patients treated with EGb 761 and in 70% receiving betahistine.
With 27 adverse events in 19 patients, EGb 761 showed better tolerability than betahistine with 39 adverse events in 31 patients.
In conclusion, the two drugs were similarly effective in the treatment of vertigo, but EGb 761 was better tolerated.
This trial is registered with controlled-trials.com ISRCTN02262139.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sokolova, Larysa& Hoerr, Robert& Mishchenko, Tamara. 2014. Treatment of Vertigo : A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine. International Journal of Otolaryngology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490162
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sokolova, Larysa…[et al.]. Treatment of Vertigo : A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine. International Journal of Otolaryngology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-490162
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sokolova, Larysa& Hoerr, Robert& Mishchenko, Tamara. Treatment of Vertigo : A Randomized, Double-Blind Trial Comparing Efficacy and Safety of Ginkgo biloba Extract EGb 761 and Betahistine. International Journal of Otolaryngology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-490162
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-490162
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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