Repetitive Electric Stimulation Elicits Enduring Improvement of Sensorimotor Performance in Seniors

الملخص EN

Age-related changes occur on all stages of the human somatosensory pathway, thereby deteriorating tactile, haptic, and sensorimotor performance.

However, recent studies show that age-related changes are not irreversible but treatable through peripheral stimulation paradigms based on neuroplasticity mechanisms.

We here applied repetitive electric stimulation (rES) to the fingers on a bi-weekly basis for 4 weeks to induce enduring amelioration of age-related changes in healthy individuals aged 60–85 years.

Tactile, haptic, and motor performance gradually improved over time of intervention.

After termination of rES, tactile acuity recovered to baseline within 2 weeks, while the gains in haptic and motor performance were preserved for 2 weeks.

Sham stimulation showed no comparable changes.

Our data indicate that age-related decline of sensorimotor performance can be ameliorated by rES and can be stabilized by the repeated application.

Thus, long-term application of rES appears as a prime candidate for maintaining sensorimotor functions in elderly individuals.