Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation
المؤلفون المشاركون
Novo, Giuseppina
Evola, Salvatore
Montaina, Carla
Novo, Salvatore
Macaione, Francesca
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-06-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
This study aimed to assess if proton pump inhibitors (PPIs) may reduce the effectiveness of clopidogrel, than H2 antagonist (anti-H2) in order to determine rehospitalization for acute coronary syndrome (re-ACS), target vessel revascularization (TVR) and cardiac death.
This case-control study included 176 patients with ACS undergoing angioplasty (PCI) with drug-eluting stent implantation.
The population was divided into two groups: PPI group (n=121) consisting of patients receiving at discharge dual antiplatelet therapy (DAT) plus PPI and anti-H2 group (n=55), consisting of patients receiving at discharge DAT + H2 receptor antagonist (H2RA).
In a followup of 36 months the prevalence of ACS event (P=0.014), TVR (P=0.031) was higher in the PPI group than in the anti-H2 group; instead there was no statistically significant difference between groups for death.
The variables independently associated with ACS were the diabetes, omeprazole, and esomeprazole; instead the variables independently associated with TVR were only omeprazole.
Our data shows that the use of omeprazole and esomeprazole, with clopidogrel, is associated with increased risk of adverse outcomes after PCI with drug-eluting stent implantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Macaione, Francesca& Montaina, Carla& Evola, Salvatore& Novo, Giuseppina& Novo, Salvatore. 2012. Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation. ISRN Cardiology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491040
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Macaione, Francesca…[et al.]. Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation. ISRN Cardiology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-491040
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Macaione, Francesca& Montaina, Carla& Evola, Salvatore& Novo, Giuseppina& Novo, Salvatore. Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation. ISRN Cardiology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-491040
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-491040
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر